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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CANX All Species: 0
Human Site: S112 Identified Species: 0
UniProt: P27824 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27824 NP_001019820.1 592 67568 S112 E V E E M K E S K L P G D K G
Chimpanzee Pan troglodytes XP_001151304 592 67554
Rhesus Macaque Macaca mulatta XP_001101429 592 67582
Dog Lupus familis XP_533285 610 69806
Cat Felis silvestris
Mouse Mus musculus P35564 591 67259
Rat Rattus norvegicus P35565 591 67236
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506871 598 67609
Chicken Gallus gallus NP_001025791 599 68090
Frog Xenopus laevis NP_001080326 611 69964
Zebra Danio Brachydanio rerio NP_998613 600 67856
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34652 619 69189
Sea Urchin Strong. purpuratus XP_791226 591 66512
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P29402 530 60468
Baker's Yeast Sacchar. cerevisiae P27825 502 56949
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.6 59.1 N.A. 93 93.5 N.A. 85.7 82.8 78.2 70.8 N.A. 31.7 N.A. 40.5 53.7
Protein Similarity: 100 99.8 99.4 75.2 N.A. 96.6 97.4 N.A. 93.1 90.8 86.2 84.1 N.A. 44.7 N.A. 58.9 69.7
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 N.A. 0 0
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 N.A. 0 0
Percent
Protein Identity: N.A. 29.3 N.A. 40 25.6 N.A.
Protein Similarity: N.A. 44.4 N.A. 53.5 41.2 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 0 N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % D
% Glu: 100 0 100 100 0 0 100 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 100 0 0 100 0 0 0 0 100 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % L
% Met: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _